Hi @Mike-Berry!
Exciting that you get to start on this journey! @wes-bryan has brought up a lot of what I would say. Pick a hypervisor, get some ISO's and get started poking around. I have recently started my journey with creating a Home Lab as well and I am documenting everything in this ITPro TV forum post right now (with plans to through them onto a Google Site using my personal Google Workspace domain):
https://forums.acilearning.com/topic/4515/home-lab-for-skills-buidling/24
I just finished Episode 2 where I go through installing a VM using Proxmox. I try my best to explain my rationale with whatever choices I make and go through my troubleshooting steps when I run into issues.
For backup software I can recommend Veeam for Home for your learning. Veeam is a backup solution that is used by a good chunk of Enterprises in the wild and could very well be a good solution for your NfP, depending on pricing of course.
I would also like to advise you that if you have questions on a server technology to check out the Server+ videos on the ITPro Platform. Wes and Ronnie do an amazing job with that series and they helped me pass my Server+ exam back in October 2023. Also, don't be afraid to ask questions here on the forum! I'm trying to be active here and would be more than happy to give my expertise, or at the very least, my Google-Fu skills for any question you may have.
Good luck with your journey, and, most importantly, have fun!